শুক্রবার, ৮ জুন, ২০১২

Millions in U.S. gear going to waste in Pakistan

[ [ [['Connery is an experienced stuntman', 2]], 'http://yhoo.it/KeQd0p', '[Slideshow: See photos taken on the way down]', ' ', '630', ' ', ' ', ], [ [['Connery is an experienced stuntman', 7]], ' http://yhoo.it/KpUoHO', '[Slideshow: Death-defying daredevils]', ' ', '630', ' ', ' ', ], [ [['know that we have confidence in', 3]], 'http://yhoo.it/LqYjAX ', '[Related: The Secret Service guide to Cartagena]', ' ', '630', ' ', ' ', ], [ [['We picked up this other dog and', 5]], 'http://yhoo.it/JUSxvi', '[Related: 8 common dog fears, how to calm them]', ' ', '630', ' ', ' ', ], [ [['accused of running a fake hepatitis B', 5]], 'http://bit.ly/JnoJYN', '[Related: Did WH share raid details with filmmakers?]', ' ', '630', ' ', ' ', ], [ [['accused of running a fake hepatitis B', 3]], 'http://bit.ly/KoKiqJ', '[Factbox: AQAP, al-Qaeda in Yemen]', ' ', '630', ' ', ' ', ], [ [['have my contacts on or glasses', 3]], 'http://abcn.ws/KTE5AZ', '[Related: Should the murder charge be dropped?]', ' ', '630', ' ', ' ', ], [ [['have made this nation great as Sarah Palin', 5]], 'http://yhoo.it/JD7nlD', '[Related: Bristol Palin reality show debuts June 19]', ' ', '630', ' ', ' ', ], [ [['have made this nation great as Sarah Palin', 1]], 'http://bit.ly/JRPFRO', '[Related: McCain adviser who vetted Palin weighs in on VP race]', ' ', '630', ' ', ' ', ], [ [['A JetBlue flight from New York to Las Vegas', 3]], 'http://yhoo.it/GV9zpj', '[Related: View photos of the JetBlue plane in Amarillo]', ' ', '630', ' ', ' ', ], [ [['the 28-year-old neighborhood watchman who shot and killed', 15]], 'http://news.yahoo.com/photos/white-house-stays-out-of-teen-s-killing-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/cv/ip/ap/default/120411/martinzimmermen.jpg', '630', ' ', 'AP', ], [ [['Titanic', 7]], 'http://news.yahoo.com/titanic-anniversary/', ' ', 'http://l.yimg.com/a/p/us/news/editorial/b/4e/b4e5ad9f00b5dfeeec2226d53e173569.jpeg', '550', ' ', ' ', ], [ [['He was in shock and still strapped to his seat', 6]], 'http://news.yahoo.com/photos/navy-jet-crashes-in-virginia-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/cv/ip/ap/default/120406/jet_ap.jpg', '630', ' ', 'AP', ], [ [['xxxxxxxxxxxx', 11]], 'http://news.yahoo.com/photos/russian-grannies-win-bid-to-sing-at-eurovision-1331223625-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/1/56/156d92f2760dcd3e75bcd649a8b85fcf.jpeg', '500', ' ', 'AP', ] ]

[ [ [['did not go as far his colleague', 8]], '29438204', '0' ], [ [[' the 28-year-old neighborhood watchman who shot and killed', 4]], '28924649', '0' ], [ [['because I know God protects me', 14], ['Brian Snow was at a nearby credit union', 5]], '28811216', '0' ], [ [['The state news agency RIA-Novosti quoted Rosaviatsiya', 6]], '28805461', '0' ], [ [['measure all but certain to fail in the face of bipartisan', 4]], '28771014', '0' ], [ [['matter what you do in this case', 5]], '28759848', '0' ], [ [['presume laws are constitutional', 7]], '28747556', '0' ], [ [['has destroyed 15 to 25 houses', 7]], '28744868', '0' ], [ [['short answer is yes', 7]], '28746030', '0' ], [ [['opportunity to tell the real story', 7]], '28731764', '0' ], [ [['entirely respectable way to put off the searing constitutional controversy', 7]], '28723797', '0' ], [ [['point of my campaign is that big ideas matter', 9]], '28712293', '0' ], [ [['As the standoff dragged into a second day', 7]], '28687424', '0' ], [ [['French police stepped up the search', 17]], '28667224', '0' ], [ [['Seeking to elevate his candidacy back to a general', 8]], '28660934', '0' ], [ [['The tragic story of Trayvon Martin', 4]], '28647343', '0' ], [ [['Karzai will get a chance soon to express', 8]], '28630306', '0' ], [ [['powerful storms stretching', 8]], '28493546', '0' ], [ [['basic norm that death is private', 6]], '28413590', '0' ], [ [['songwriter also saw a surge in sales for her debut album', 6]], '28413590', '1', 'Watch music videos from Whitney Houston ', 'on Yahoo! Music', 'http://music.yahoo.com' ], [ [['keyword', 99999999999999999999999]], 'videoID', '1', 'overwrite-pre-description', 'overwrite-link-string', 'overwrite-link-url' ] ]

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Analysis: India frustrations send some foreign firms packing

US News

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Analysis: India frustrations send some foreign firms packing

Reuters | June 08, 2012 | 12:06 PM EDT

NEW DELHI/MUMBAI (Reuters) - Frustrated by a lack of opportunities in India, Germany's Fraport <FRAG.DE>, the world's No. 2 airport operator, is shutting its development office in the country, the latest in a growing list of companies exiting Asia's third-largest economy.

Regulatory uncertainty and policy gridlock have battered foreign corporate sentiment towards India, adding to a dramatic slowdown in economic growth and exacerbating a widening current account deficit that has knocked the rupee to record lows.

"When we came to India in 2006, we were actually extremely bullish about the market. We felt India had a lot of potential at that time," Ansgar Sickert, who heads Fraport's India operations, told Reuters in a telephone interview on Friday.

Government plans then to privatize dozens of airports in smaller cities have not come to fruition.

"We were disappointed when none of these opportunities materialized," said Sickert.

Many foreign companies in other sectors have seen their India plans thwarted by sluggish or inconsistent policymaking under the embattled government of Prime Minister Manmohan Singh.

The list of companies to leave India includes telecoms carriers Etisalat <ETEL.AD> of Abu Dhabi and Bahrain Telecommunications Co <BTEL.BH>, whose licenses were among those ordered cancelled by an Indian court amid a corruption probe.

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বৃহস্পতিবার, ৭ জুন, ২০১২

Without a scratch: New American Chemical Society video on self-healing plastics

Without a scratch: New American Chemical Society video on self-healing plastics [ Back to EurekAlert! ] Public release date: 7-Jun-2012
[ | E-mail | Share Share ]

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society

WASHINGTON, June 7, 2012 A new American Chemical Society (ACS) video explores materials that mimic the human skin's ability to heal scratches and cuts in the latest episode of its award-winning Bytesize Science series. The video is available at www.bytesizescience.com.

The video takes viewers on a tour of the lab of Nancy Sottos, Ph.D., who has published articles on the self-healing plastics in a number of ACS peer-reviewed scientific journals. She is an engineering professor at the University of Illinois at UrbanaChampaign. Inspired by human skin, the plastics repair themselves by "bleeding" healing agents when they are cut or scratched.

This development offers the promise of cell phones, laptops, cars and other products with self-repairing, longer-lasting surfaces. However, Sottos anticipates that it may be awhile before the self-healing technology is widely used in electronic goods. She expects it will first be used in more durable, self-healing paints and coatings.

###

For additional entertaining video podcasts from ACS, go to www.bytesizescience.com. The Bytesize Science series is produced by the ACS Office of Public Affairs.

For more entertaining, informative science videos and podcasts from the ACS Office of Public Affairs, view Prized Science, Spellbound, Science Elements and Global Challenges/Chemistry Solutions.

The American Chemical Society is a non-profit organization chartered by the U.S. Congress. With more than 164,000 members, ACS is the world's largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.

To automatically receive news releases from the American Chemical Society, contact newsroom@acs.org.



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Without a scratch: New American Chemical Society video on self-healing plastics [ Back to EurekAlert! ] Public release date: 7-Jun-2012
[ | E-mail | Share Share ]

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society

WASHINGTON, June 7, 2012 A new American Chemical Society (ACS) video explores materials that mimic the human skin's ability to heal scratches and cuts in the latest episode of its award-winning Bytesize Science series. The video is available at www.bytesizescience.com.

The video takes viewers on a tour of the lab of Nancy Sottos, Ph.D., who has published articles on the self-healing plastics in a number of ACS peer-reviewed scientific journals. She is an engineering professor at the University of Illinois at UrbanaChampaign. Inspired by human skin, the plastics repair themselves by "bleeding" healing agents when they are cut or scratched.

This development offers the promise of cell phones, laptops, cars and other products with self-repairing, longer-lasting surfaces. However, Sottos anticipates that it may be awhile before the self-healing technology is widely used in electronic goods. She expects it will first be used in more durable, self-healing paints and coatings.

###

For additional entertaining video podcasts from ACS, go to www.bytesizescience.com. The Bytesize Science series is produced by the ACS Office of Public Affairs.

For more entertaining, informative science videos and podcasts from the ACS Office of Public Affairs, view Prized Science, Spellbound, Science Elements and Global Challenges/Chemistry Solutions.

The American Chemical Society is a non-profit organization chartered by the U.S. Congress. With more than 164,000 members, ACS is the world's largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.

To automatically receive news releases from the American Chemical Society, contact newsroom@acs.org.



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


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ScienceDaily: Biochemistry News

ScienceDaily: Biochemistry Newshttp://www.sciencedaily.com/news/matter_energy/biochemistry/ Read the latest research in biochemistry -- protein structure and function, RNA and DNA, enzymes and biosynthesis and more biochemistry news.en-usThu, 07 Jun 2012 15:05:02 EDTThu, 07 Jun 2012 15:05:02 EDT60ScienceDaily: Biochemistry Newshttp://www.sciencedaily.com/images/logosmall.gifhttp://www.sciencedaily.com/news/matter_energy/biochemistry/ For more science articles, visit ScienceDaily.Photosynthesis: A new way of looking at photosystem IIhttp://www.sciencedaily.com/releases/2012/06/120606155808.htm Using ultrafast, intensely bright pulses of X-rays scientists have obtained the first ever images at room temperature of photosystem II, a protein complex critical for photosynthesis and future artificial photosynthetic systems.Wed, 06 Jun 2012 15:58:58 EDThttp://www.sciencedaily.com/releases/2012/06/120606155808.htm1 million billion billion billion billion billion billion: Number of undiscovered drugshttp://www.sciencedaily.com/releases/2012/06/120606132316.htm A new voyage into "chemical space" ? occupied not by stars and planets but substances that could become useful in everyday life ? has concluded that scientists have synthesized barely one tenth of one percent of potential medicines. The report estimates that the actual number of these so-called "small molecules" could be one novemdecillion (that's one with 60 zeroes), more than some estimates of the number of stars in the universe.Wed, 06 Jun 2012 13:23:23 EDThttp://www.sciencedaily.com/releases/2012/06/120606132316.htmHalogen bonding helps design new drugshttp://www.sciencedaily.com/releases/2012/06/120605121639.htm Halogens particularly chlorine, bromine, and iodine ? have a unique quality which allows them to positively influence the interaction between molecules. This ?halogen bonding? has been employed in the area of materials science for some time, but is only now finding applications in the life sciences.Tue, 05 Jun 2012 12:16:16 EDThttp://www.sciencedaily.com/releases/2012/06/120605121639.htmFaster, more sensitive photodetector created by tricking graphenehttp://www.sciencedaily.com/releases/2012/06/120605102842.htm Researchers have developed a highly sensitive detector of infrared light that can be used in applications ranging from detection of chemical and biochemical weapons from a distance and better airport body scanners to chemical analysis in the laboratory and studying the structure of the universe through new telescopes.Tue, 05 Jun 2012 10:28:28 EDThttp://www.sciencedaily.com/releases/2012/06/120605102842.htmFilming life in the fast lanehttp://www.sciencedaily.com/releases/2012/06/120604092858.htm A new microscope enabled scientists to film a fruit fly embryo, in 3D, from when it was about two-and-a-half hours old until it walked away from the microscope as a larva.Mon, 04 Jun 2012 09:28:28 EDThttp://www.sciencedaily.com/releases/2012/06/120604092858.htmExpanding the genetic alphabet may be easier than previously thoughthttp://www.sciencedaily.com/releases/2012/06/120603191722.htm A new study suggests that the replication process for DNA -- the genetic instructions for living organisms that is composed of four bases (C, G, A and T) -- is more open to unnatural letters than had previously been thought. An expanded "DNA alphabet" could carry more information than natural DNA, potentially coding for a much wider range of molecules and enabling a variety of powerful applications, from precise molecular probes and nanomachines to useful new life forms.Sun, 03 Jun 2012 19:17:17 EDThttp://www.sciencedaily.com/releases/2012/06/120603191722.htmNanotechnology breakthrough could dramatically improve medical testshttp://www.sciencedaily.com/releases/2012/05/120531165752.htm A laboratory test used to detect disease and perform biological research could be made more than 3 million times more sensitive, according to researchers who combined standard biological tools with a breakthrough in nanotechnology.Thu, 31 May 2012 16:57:57 EDThttp://www.sciencedaily.com/releases/2012/05/120531165752.htmX-ray laser probes biomolecules to individual atomshttp://www.sciencedaily.com/releases/2012/05/120531145728.htm Scientists have demonstrated how the world's most powerful X-ray laser can assist in cracking the structures of biomolecules, and in the processes helped to pioneer critical new investigative avenues in biology.Thu, 31 May 2012 14:57:57 EDThttp://www.sciencedaily.com/releases/2012/05/120531145728.htmBuilding molecular 'cages' to fight diseasehttp://www.sciencedaily.com/releases/2012/05/120531145720.htm Biochemists have designed specialized proteins that assemble themselves to form tiny molecular cages hundreds of times smaller than a single cell. The creation of these miniature structures may be the first step toward developing new methods of drug delivery or even designing artificial vaccines.Thu, 31 May 2012 14:57:57 EDThttp://www.sciencedaily.com/releases/2012/05/120531145720.htmFree-electron lasers reveal detailed architecture of proteinshttp://www.sciencedaily.com/releases/2012/05/120531145630.htm Ultrashort flashes of X-radiation allow atomic structures of macromolecules to be obtained even from tiny protein crystals.Thu, 31 May 2012 14:56:56 EDThttp://www.sciencedaily.com/releases/2012/05/120531145630.htmRewriting DNA to understand what it sayshttp://www.sciencedaily.com/releases/2012/05/120531102207.htm Our ability to "read" DNA has made tremendous progress in the past few decades, but the ability to understand and alter the genetic code, that is, to "rewrite" the DNA-encoded instructions, has lagged behind. A new study advances our understanding of the genetic code: It proposes a way of effectively introducing numerous carefully planned DNA segments into genomes of living cells and of testing the effects of these changes. New technology speeds up DNA "rewriting" and measures the effects of the changes in living cells.Thu, 31 May 2012 10:22:22 EDThttp://www.sciencedaily.com/releases/2012/05/120531102207.htmNanodevice manufacturing strategy using DNA 'Building blocks'http://www.sciencedaily.com/releases/2012/05/120530152203.htm Researchers have developed a method for building complex nanostructures out of interlocking DNA "building blocks" that can be programmed to assemble themselves into precisely designed shapes. With further development, the technology could one day enable the creation of new nanoscale devices that deliver drugs directly to disease sites.Wed, 30 May 2012 15:22:22 EDThttp://www.sciencedaily.com/releases/2012/05/120530152203.htmBioChip may make diagnosis of leukemia and HIV faster, cheaperhttp://www.sciencedaily.com/releases/2012/05/120530104034.htm Inexpensive, portable devices that can rapidly screen cells for leukemia or HIV may soon be possible thanks to a chip that can produce three-dimensional focusing of a stream of cells, according to researchers.Wed, 30 May 2012 10:40:40 EDThttp://www.sciencedaily.com/releases/2012/05/120530104034.htmCellular computers? Scientists train cells to perform boolean functionshttp://www.sciencedaily.com/releases/2012/05/120530100041.htm Scientists have engineered cells that behave like AND and OR Boolean logic gates, producing an output based on one or more unique inputs. This feat could eventually help researchers create computers that use cells as tiny circuits.Wed, 30 May 2012 10:00:00 EDThttp://www.sciencedaily.com/releases/2012/05/120530100041.htmIon-based electronic chip to control muscles: Entirely new circuit technology based on ions and moleculeshttp://www.sciencedaily.com/releases/2012/05/120529113543.htm An integrated chemical chip has just been developed. An advantage of chemical circuits is that the charge carrier consists of chemical substances with various functions. This means that we now have new opportunities to control and regulate the signal paths of cells in the human body. The chemical chip can control the delivery of the neurotransmitter acetylcholine. This enables chemical control of muscles, which are activated when they come into contact with acetylcholine.Tue, 29 May 2012 11:35:35 EDThttp://www.sciencedaily.com/releases/2012/05/120529113543.htmMethod for building artificial tissue devisedhttp://www.sciencedaily.com/releases/2012/05/120528154859.htm Physicists have developed a method that models biological cell-to-cell adhesion that could also have industrial applications.Mon, 28 May 2012 15:48:48 EDThttp://www.sciencedaily.com/releases/2012/05/120528154859.htmSmallest possible five-ringed structure made: 'Olympicene' molecule built using clever synthetic organic chemistryhttp://www.sciencedaily.com/releases/2012/05/120528100253.htm Scientists have created and imaged the smallest possible five-ringed structure -- about 100,000 times thinner than a human hair. Dubbed 'olympicene', the single molecule was brought to life in a picture thanks to a combination of clever synthetic chemistry and state-of-the-art imaging techniques.Mon, 28 May 2012 10:02:02 EDThttp://www.sciencedaily.com/releases/2012/05/120528100253.htm'Unzipped' carbon nanotubes could help energize fuel cells and batterieshttp://www.sciencedaily.com/releases/2012/05/120527153818.htm Multi-walled carbon nanotubes riddled with defects and impurities on the outside could replace some of the expensive platinum catalysts used in fuel cells and metal-air batteries, according to scientists.Sun, 27 May 2012 15:38:38 EDThttp://www.sciencedaily.com/releases/2012/05/120527153818.htmSuper-sensitive tests could detect diseases earlierhttp://www.sciencedaily.com/releases/2012/05/120527153718.htm Scientists have developed an ultra-sensitive test that should enable them to detect signs of a disease in its earliest stages.Sun, 27 May 2012 15:37:37 EDThttp://www.sciencedaily.com/releases/2012/05/120527153718.htmCell?s transport pods look like a molecular version of robots from Transformershttp://www.sciencedaily.com/releases/2012/05/120525103614.htm Images of the cell's transport pods have revealed a molecular version of the robots from Transformers. Previously, scientists had been able to create and determine the structure of 'cages' formed by parts of the protein coats that encase other types of vesicles, but this study was the first to obtain high-resolution images of complete vesicles, budded from a membrane.Fri, 25 May 2012 10:36:36 EDThttp://www.sciencedaily.com/releases/2012/05/120525103614.htmDiscarded data may hold the key to a sharper view of moleculeshttp://www.sciencedaily.com/releases/2012/05/120524143527.htm There's nothing like a new pair of eyeglasses to bring fine details into sharp relief. For scientists who study the large molecules of life from proteins to DNA, the equivalent of new lenses have come in the form of an advanced method for analyzing data from X-ray crystallography experiments.Thu, 24 May 2012 14:35:35 EDThttp://www.sciencedaily.com/releases/2012/05/120524143527.htmNewly modified nanoparticle opens window on future gene editing technologieshttp://www.sciencedaily.com/releases/2012/05/120524123232.htm Researchers are using nanoparticles to simultaneously deliver proteins and DNA into plant cells. The technology could allow more sophisticated and targeted editing of plant genomes. And that could help researchers develop crops that adapt to changing climates and resist pests.Thu, 24 May 2012 12:32:32 EDThttp://www.sciencedaily.com/releases/2012/05/120524123232.htmUnusual quantum effect discovered in earliest stages of photosynthesishttp://www.sciencedaily.com/releases/2012/05/120524092932.htm Quantum physics and plant biology seem like two branches of science that could not be more different, but surprisingly they may in fact be intimately tied. Scientists have discovered an unusual quantum effect in the earliest stages of photosynthesis.Thu, 24 May 2012 09:29:29 EDThttp://www.sciencedaily.com/releases/2012/05/120524092932.htmBig step toward quantum computing: Efficient and tunable interface for quantum networkshttp://www.sciencedaily.com/releases/2012/05/120523135527.htm Quantum computers may someday revolutionize the information world. But in order for quantum computers at distant locations to communicate with one another, they have to be linked together in a network. While several building blocks for a quantum computer have already been successfully tested in the laboratory, a network requires one additonal component: A reliable interface between computers and information channels. Austrian physicists now report the construction of an efficient and tunable interface for quantum networks.Wed, 23 May 2012 13:55:55 EDThttp://www.sciencedaily.com/releases/2012/05/120523135527.htmRapid DNA sequencing may soon be routine part of each patient's medical recordhttp://www.sciencedaily.com/releases/2012/05/120522152655.htm Rapid DNA sequencing may soon become a routine part of each individual's medical record, providing enormous information previously sequestered in the human genome's 3 billion nucleotide bases. Recent advances in sequencing technology using a tiny orifice known as a nanopore are covered in a new a article.Tue, 22 May 2012 15:26:26 EDThttp://www.sciencedaily.com/releases/2012/05/120522152655.htmMethod to strengthen proteins with polymershttp://www.sciencedaily.com/releases/2012/05/120521164104.htm Scientists have synthesized polymers to attach to proteins in order to stabilize them during shipping, storage and other activities. The study findings suggest that these polymers could be useful in stabilizing protein formulations.Mon, 21 May 2012 16:41:41 EDThttp://www.sciencedaily.com/releases/2012/05/120521164104.htmTotally RAD: Bioengineers create rewritable digital data storage in DNAhttp://www.sciencedaily.com/releases/2012/05/120521163751.htm Scientists have devised a method for repeatedly encoding, storing and erasing digital data within the DNA of living cells. In practical terms, they have devised the genetic equivalent of a binary digit -- a "bit" in data parlance.Mon, 21 May 2012 16:37:37 EDThttp://www.sciencedaily.com/releases/2012/05/120521163751.htmDon't like blood tests? New microscope uses rainbow of light to image the flow of individual blood cellshttp://www.sciencedaily.com/releases/2012/05/120521115654.htm Blood tests convey vital medical information, but the sight of a needle often causes anxiety and results take time. A new device however, can reveal much the same information as a traditional blood test in real-time, simply by shining a light through the skin. This portable optical instrument is able to provide high-resolution images of blood coursing through veins without the need for harsh fluorescent dyes.Mon, 21 May 2012 11:56:56 EDThttp://www.sciencedaily.com/releases/2012/05/120521115654.htmZooming in on bacterial weapons in 3-D: Structure of bacterial injection needles deciphered at atomic resolutionhttp://www.sciencedaily.com/releases/2012/05/120521103808.htm The plague, bacterial dysentery, and cholera have one thing in common: These dangerous diseases are caused by bacteria which infect their host using a sophisticated injection apparatus. Through needle-like structures, they release molecular agents into their host cell, thereby evading the immune response. Researchers have now elucidated the structure of such a needle at atomic resolution. Their findings might contribute to drug tailoring and the development of strategies which specifically prevent the infection process.Mon, 21 May 2012 10:38:38 EDThttp://www.sciencedaily.com/releases/2012/05/120521103808.htmEngineers use droplet microfluidics to create glucose-sensing microbeadshttp://www.sciencedaily.com/releases/2012/05/120518132657.htm Tiny beads may act as minimally invasive glucose sensors for a variety of applications in cell culture systems and tissue engineering.Fri, 18 May 2012 13:26:26 EDThttp://www.sciencedaily.com/releases/2012/05/120518132657.htmChemists merge experimentation with theory in understanding of water moleculehttp://www.sciencedaily.com/releases/2012/05/120518081147.htm Using newly developed imaging technology, chemists have confirmed years of theoretical assumptions about water molecules, the most abundant and one of the most frequently studied substances on Earth.Fri, 18 May 2012 08:11:11 EDThttp://www.sciencedaily.com/releases/2012/05/120518081147.htmDiamond used to produce graphene quantum dots and nano-ribbons of controlled structurehttp://www.sciencedaily.com/releases/2012/05/120517193141.htm Researchers have come closer to solving an old challenge of producing graphene quantum dots of controlled shape and size at large densities, which could revolutionize electronics and optoelectronics.Thu, 17 May 2012 19:31:31 EDThttp://www.sciencedaily.com/releases/2012/05/120517193141.htmIn chemical reactions, water adds speed without heathttp://www.sciencedaily.com/releases/2012/05/120517143506.htm Scientists have discovered how adding trace amounts of water can tremendously speed up chemical reactions -? such as hydrogenation and hydrogenolysis ?- in which hydrogen is one of the reactants, or starting materials.Thu, 17 May 2012 14:35:35 EDThttp://www.sciencedaily.com/releases/2012/05/120517143506.htmPlant protein discovery could boost bioeconomyhttp://www.sciencedaily.com/releases/2012/05/120514104848.htm Three proteins have been found to be involved in the accumulation of fatty acids in plants. The discovery could help plant scientists boost seed oil production in crops. And that could boost the production of biorenewable fuels and chemicals.Mon, 14 May 2012 10:48:48 EDThttp://www.sciencedaily.com/releases/2012/05/120514104848.htmPhotonics: New approach to generating terahertz radiation will lead to new imaging and sensing applicationshttp://www.sciencedaily.com/releases/2012/05/120510095622.htm A new approach to generating terahertz radiation will lead to new imaging and sensing applications. The low energy of the radiation means that it can pass through materials that are otherwise opaque, opening up uses in imaging and sensing ? for example, in new security scanners. In practice, however, applications have been difficult to implement.Thu, 10 May 2012 09:56:56 EDThttp://www.sciencedaily.com/releases/2012/05/120510095622.htmIt's a trap: New lab technique captures microRNA targetshttp://www.sciencedaily.com/releases/2012/05/120509135959.htm To better understand how microRNAs -- small pieces of genetic material -- influence human health and disease, scientists first need to know which microRNAs act upon which genes. To do this scientists developed miR-TRAP, a new easy-to-use method to directly identify microRNA targets in cells.Wed, 09 May 2012 13:59:59 EDThttp://www.sciencedaily.com/releases/2012/05/120509135959.htmQuantum dots brighten the future of lightinghttp://www.sciencedaily.com/releases/2012/05/120508173349.htm Researchers have boosted the efficiency of a novel source of white light called quantum dots more than tenfold, making them of potential interest for commercial applications.Tue, 08 May 2012 17:33:33 EDThttp://www.sciencedaily.com/releases/2012/05/120508173349.htmMolecular container gives drug dropouts a second chancehttp://www.sciencedaily.com/releases/2012/05/120508152129.htm Chemists have designed a molecular container that can hold drug molecules and increase their solubility, in one case up to nearly 3,000 times.Tue, 08 May 2012 15:21:21 EDThttp://www.sciencedaily.com/releases/2012/05/120508152129.htmUltrasound idea: Prototype bioreactor evaluates engineered tissue while creating ithttp://www.sciencedaily.com/releases/2012/05/120503194229.htm Researchers have developed a prototype bioreactor that both stimulates and evaluates tissue as it grows, mimicking natural processes while eliminating the need to stop periodically to cut up samples for analysis.Thu, 03 May 2012 19:42:42 EDThttp://www.sciencedaily.com/releases/2012/05/120503194229.htmNew technique generates predictable complex, wavy shapes: May explain brain folds and be useful for drug deliveryhttp://www.sciencedaily.com/releases/2012/05/120503120130.htm A new technique predictably generates complex, wavy shapes and may help improve drug delivery and explain natural patterns from brain folds to bell peppers.Thu, 03 May 2012 12:01:01 EDThttp://www.sciencedaily.com/releases/2012/05/120503120130.htmAt smallest scale, liquid crystal behavior portends new materialshttp://www.sciencedaily.com/releases/2012/05/120502132953.htm Liquid crystals, the state of matter that makes possible the flat screen technology now commonly used in televisions and computers, may have some new technological tricks in store.Wed, 02 May 2012 13:29:29 EDThttp://www.sciencedaily.com/releases/2012/05/120502132953.htmElectronic nanotube nose out in fronthttp://www.sciencedaily.com/releases/2012/05/120502112910.htm A new nanotube super sensor is able to detect subtle differences with a single sniff. For example, the chemical dimethylsulfone is associated with skin cancer. 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The technique uses silk fibers to reinforce a silk matrix. Adding microfibers to the scaffolds enhances bone formation and mechanical properties. It could improve repair after accident or disease.Mon, 30 Apr 2012 15:17:17 EDThttp://www.sciencedaily.com/releases/2012/04/120430151752.htmMolecular spectroscopy tracks living mammalian cells in real time as they differentiatehttp://www.sciencedaily.com/releases/2012/04/120430114937.htm Cells regulate their functions by adding or subtracting phosphates from proteins. If scientists could study the process in detail, in individual cells over time, understanding and treating diseases would be greatly aided. 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These results could help scientists to understand phenomena that occur on surfaces such as those of large biological molecules.Mon, 30 Apr 2012 10:53:53 EDThttp://www.sciencedaily.com/releases/2012/04/120430105356.htmBejeweled: Nanotech gets boost from nanowire decorationshttp://www.sciencedaily.com/releases/2012/04/120427100113.htm Engineers have found a novel method for "decorating" nanowires with chains of tiny particles to increase their electrical and catalytic performance. The new technique is simpler, faster and more effective than earlier methods and could lead to better batteries, solar cells and catalysts.Fri, 27 Apr 2012 10:01:01 EDThttp://www.sciencedaily.com/releases/2012/04/120427100113.htmFirst custom designed protein crystal createdhttp://www.sciencedaily.com/releases/2012/04/120425140403.htm Protein design is technique that is increasingly valuable to a variety of fields, from biochemistry to therapeutics to materials engineering. Chemists have taken this kind of design a step further; Using computational methods, they have created the first custom-designed protein crystal.Wed, 25 Apr 2012 14:04:04 EDThttp://www.sciencedaily.com/releases/2012/04/120425140403.htmCompressed sensing allows imaging of live cell structureshttp://www.sciencedaily.com/releases/2012/04/120423104019.htm Researchers have advanced the ability to view a clear picture of a single cellular structure in motion. By identifying molecules using compressed sensing, this new method provides needed spatial resolution plus a faster temporal resolution.Mon, 23 Apr 2012 10:40:40 EDThttp://www.sciencedaily.com/releases/2012/04/120423104019.htmWhat did the scientist say to the sommelier? 'Show me the proof'http://www.sciencedaily.com/releases/2012/04/120422162415.htm What does lemon pan sauce chicken have to do with biochemistry and molecular biology? Some will say that successful execution of the dish requires the Maillard reaction, a chemical process that's responsible for the flavors and colors in a variety of food.Sun, 22 Apr 2012 16:24:24 EDThttp://www.sciencedaily.com/releases/2012/04/120422162415.htmChemists explain the molecular workings of promising fuel cell electrolytehttp://www.sciencedaily.com/releases/2012/04/120422134953.htm Researchers have revealed how protons move in phosphoric acid in a study that sheds new light on the workings of a promising fuel cell electrolyte.Sun, 22 Apr 2012 13:49:49 EDThttp://www.sciencedaily.com/releases/2012/04/120422134953.htmFirst atomic-scale real-time movies of platinum nanocrystal growth in liquidshttp://www.sciencedaily.com/releases/2012/04/120419132602.htm Researchers have developed a technique for encapsulating liquids of nanocrystals between layers of graphene so that chemical reactions in the liquids can be imaged with an electron microscope. With this technique, movies can be made that provide unprecedented direct observations of physical, chemical and biological phenomena that take place in liquids on the nanometer scale.Thu, 19 Apr 2012 13:26:26 EDThttp://www.sciencedaily.com/releases/2012/04/120419132602.htmDefending against chemical acts of terrorismhttp://www.sciencedaily.com/releases/2012/04/120419121523.htm Researchers may have found a way to protect us against otherwise deadly chemical attacks, such as the subway sarin incident in Tokyo that left thirteen people dead and thousands more injured or with temporary vision problems. The method is based on a new and improved version of a detoxifying enzyme produced naturally by our livers, according to a new reportThu, 19 Apr 2012 12:15:15 EDThttp://www.sciencedaily.com/releases/2012/04/120419121523.htmNature's billion-year-old battery key to storing energyhttp://www.sciencedaily.com/releases/2012/04/120418143757.htm New research is bringing us one step closer to clean energy. It is possible to extend the length of time a battery-like enzyme can store energy from seconds to hours, a new study shows.Wed, 18 Apr 2012 14:37:37 EDThttp://www.sciencedaily.com/releases/2012/04/120418143757.htmAdvance could mean stain-busting super scrub brushes and other new laundry productshttp://www.sciencedaily.com/releases/2012/04/120418135259.htm Scientists are reporting development and successful testing of a way to reuse -- hundreds of times -- the expensive, dirt-busting enzymes that boost the cleaning power of laundry detergents and powdered bleaches that now disappear down the drain. The discovery opens the door to new laundry products, like special scrub brushes or reusable enzyme-coated plastic flakes and strips that might be added to cheaper detergents.Wed, 18 Apr 2012 13:52:52 EDThttp://www.sciencedaily.com/releases/2012/04/120418135259.htmEarly detection techniques offer hope for improved outcomes in lung cancer patientshttp://www.sciencedaily.com/releases/2012/04/120418095347.htm New techniques for identifying lung cancer earlier ?- including a new type of chest screening, a nanotech ?nose? and a method to examine the cells of the cheek -- are showing substantial promise, according to new research.Wed, 18 Apr 2012 09:53:53 EDThttp://www.sciencedaily.com/releases/2012/04/120418095347.htmFirst description of a triple DNA helix in vacuumhttp://www.sciencedaily.com/releases/2012/04/120418095315.htm Scientists have managed for the first time to extract trustworthy structural information from a triple helix DNA in gas phase, that is to say in conditions in which DNA is practically in a vacuum. This research could bring the development of antigen therapy based on these DNA structures closer.Wed, 18 Apr 2012 09:53:53 EDThttp://www.sciencedaily.com/releases/2012/04/120418095315.htmNew process improves catalytic rate of enzymes by 3,000 percenthttp://www.sciencedaily.com/releases/2012/04/120417152732.htm Light of specific wavelengths can be used to boost an enzyme's function by as much as 30 fold, potentially establishing a path to less expensive biofuels, detergents and a host of other products.Tue, 17 Apr 2012 15:27:27 EDThttp://www.sciencedaily.com/releases/2012/04/120417152732.htmHot new manufacturing tool: A temperature-controlled microbehttp://www.sciencedaily.com/releases/2012/04/120417080533.htm Scientists have found a way to control a heat-loving microbe with a temperature switch: it makes a product at low temperatures but not at high temperatures. The innovation could make it easier to use microorganisms as miniature factories for the production of needed materials like biofuels.Tue, 17 Apr 2012 08:05:05 EDThttp://www.sciencedaily.com/releases/2012/04/120417080533.htm

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Emboldened conservative activists to gather in Chicago after Wis. victory

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Shuttle Enterprise arrives at NYC's Intrepid

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Long-jailed China labor activist said to kill self

(AP) ? An ailing Chinese labor activist imprisoned for two decades, some of it doing hard labor, died in a hospital Wednesday, reportedly hanging himself one year after being released from jail.

Li Wangyang had advocated for independent labor unions in central China's Hunan province and was caught in the sweeping nationwide crackdown on all forms of dissent after the Tiananmen Square democracy protests were quashed in 1989.

Brother-in-law Zhao Baozhu said he was suspicious about Li's death because the activist had never expressed a desire to kill himself despite spending 20 years in prison and being very sick. He said that Li had seemed normal over dinner the previous night.

"He was always very strong, there was no sign at all that he was thinking of killing himself," Zhao told The Associated Press. "Even though he had so many illnesses and spent more than 20 years in jail, he never talked about suicide. So I don't believe it."

Li was already dead by the time Zhao got to the hospital in Shaoyang city on Wednesday morning after being notified of Li's death by the facility. He was 62.

Li was on his feet next to his bed in a hospital, with a white strip of cloth tied tightly around his neck and connected to a window bar above, Zhao said.

His brother-in-law did not cite other reasons for his doubts Li committed suicide, but some activists, looking at photos on the Internet of Li's hanging, said they thought it was unusual that his feet were touching the ground.

Phones rang unanswered at the Daxiang District People's Hospital, where Li was being treated for illnesses including heart disease, diabetes, failing eyesight and hearing.

Li was arrested for his labor activism on June 9, 1989, five days after the bloody military crackdown on protesters in Beijing's Tiananment Square. Sentenced for "counterrevolutionary propaganda and incitement," he spent much of his 11-year term at hard labor.

The subsequent, 10-year sentence for inciting subversion centered on his demands for government help for health problems caused by beatings and mistreatment in prison.

During his first prison term, Li was held in solitary confinement at times and beaten so badly that he had to be hospitalized, according to Human Rights in China.

Li's death was being mourned on Twitter by various activists, including prominent rights lawyer Teng Biao, who posted a picture of calligraphy scrolls he dedicated to Li that said: "An inch of blood for an inch of freedom, thousands of miles of rivers bring thousands of miles of woes."

___

Follow Gillian Wong on Twitter at http://twitter.com/gillianwong

Associated Press

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Russia says not in talks on Assad's exit

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মঙ্গলবার, ৫ জুন, ২০১২

Acquiring A Toy Retail Store

This article has been viewed 10 times.

Maintaining a toy shop and serving children with their most precious possession, toys, is the greatest experience in the globe. The fulfillment you get when you see a youngster enjoying in your store is matchless.
If you don?t possess a store yet and wish to buy one, then read on to understand specific crucial aspects which you should keep in mind to make sure a great business deal.

Buying a toy store is a rewarding business to grab even when you think in terms of industry. There may be myriad motives for sale of companies by the proprietors; it is up to the purchaser to discover the very best business opportunity for themself that enables him gain in abundance from the same.

It is basically essential to look at the past efficiency of the retail store to distinguish its profits and potential to grow in future. The economical statements must be thoroughly read and assessed. It is useful to hire a business broker for evaluating the business for sale appropriately so as to stay away from any folly in the process of business valuation.

The capital necessary for purchase, functioning and real estate investment purposes should be determined with due consideration to the worth of property, cost of tangible goods, office expenses etc. Make sure you negotiate the selling price of the business with the owner in order to arrive at the very best figure. The enterprise should be worth what you are ready to pay for it.

You should have full knowledge about the nifty gritty of the business. You must inquire about all the sorts of merchandise and services the store deals in. The fundamental and most famous toys must be present at the store for sale. There are numerous in fashion toys that may be encouraged from celebs or from cartoons or films. They provide for a good marketing approach for the toys? business because of its ability to appeal to more customers.

It is crucial to know that your clients are kids, so, the decor of the store and the items and services should have the capability to bring in kids from far away. The advertisement must be put the best place and it should be very colorful and mesmerizing for the kids to want to own the toy after a mere look at it in print or in television.

You should also know about any special services for kids that the store offers. You must also have complete information about the working hours, holidays, special discounts, sale, season, time of rush in the store etc so that you can prepare yourself well beforehand.

The interior of the store must be colorful and lively so that the kids want to spend a lot of time inside. The staff should be friendly and skilled in arranging the goods properly on the shelves and display window. They must be able to become kids with kids. Display window should be placed with a mix of all sorts of toys so as to lure maximum customers right from outside. The location also plays an important role in the success of any business. So, the buyer should ensure to buy one at the best market place.
Such details help in getting a profitable deal that offers profits in the long run.

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Queen's Jubilee: Rock concert at Buckingham Palace

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Scientists identify mechanism for regulating plant oil production

Scientists identify mechanism for regulating plant oil production [ Back to EurekAlert! ] Public release date: 4-Jun-2012
[ | E-mail | Share Share ]

Contact: Karen McNulty Walsh
kmcnulty@bnl.gov
631-344-8350
DOE/Brookhaven National Laboratory

Findings suggest ways to increase oil production for biofuels and industrial processes

UPTON, NY - Scientists at the U.S. Department of Energy's Brookhaven National Laboratory have identified key elements in the biochemical mechanism plants use to limit the production of fatty acids. The results suggest ways scientists might target those biochemical pathways to increase the production of plant oils as a renewable resource for biofuels and industrial processes.

"Now that we understand how this system operates - how plants 'know' when they've made enough oil and how they slow down production - we can look for ways to break the feedback loop so they keep making more oil," said Brookhaven biochemist John Shanklin, leader of the group publishing the work in the Proceedings of the National Academy of Sciences the week of June 4, 2012.

Similar biochemical feedback loops regulate a wide range of metabolic processes in living things. They work similar to the way a thermostat maintains a relatively constant temperature in your home: When it gets too warm, the heating system turns off until the temperature falls to the set point, at which time it turns on again.

"There were hints that such a feedback system might exist for plant oil production," said Shanklin, who credits Carl Andre - a former postdoctoral research fellow now working at BASF Plant Science in North Carolina - with designing and carrying out the intricate biochemical detective work that uncovered the details.

"It's very difficult to work on developing oil seeds because they are very tiny," Shanklin explained. So the scientists performed their biochemical tests using a plant embryo cell culture to simulate what goes on in the seeds.

With assistance from the Radiotracer Chemistry and Biological Imaging group at Brookhaven (http://www.bnl.gov/medical/RCIBI/), Andre synthesized "labeled" forms of the fatty acids that occur as intermediates along the metabolic pathway that leads to oil production. He fed these, one at a time, to the plant cell cultures, measuring the labeled metabolites with the help of analytic chemist Richard Haslam of Rothamsted Research in the UK. They also looked to see which added intermediates would inhibit oil production.

Andre's work pointed to a fatty acid that occurs fairly late in the production process, coupled to a carrier protein (essential to making the oily substance soluble in water), as the key intermediate that puts the brakes on oil production. It's the first "desaturated" fatty acid - the first one with a double bond between two of the carbon atoms, formed after all 18 carbon atoms are added to the chain.

Then, knowing that this intermediate somehow sent the "slow-down" signal, the team sought to determine its "target" - how it actually inhibits oil synthesis. They knew from other biochemical feedback loops that the likely target would be an enzyme early in the synthesis pathway. But they wanted to figure out exactly which one.

To do this, they monitored the production process by labeling the intermediates one at a time with a radioactive form of carbon while also feeding the cells an excess of the "slow-down" signaling fatty acid. If the label from the intermediate ended up in the oil product, the "slow-down" signal had to have its effect prior to that step.

The first two experiments gave them the answer: When they labeled the first compound in the synthesis pathway, which is acetate, very little labeled carbon ended up in the oil and oil production was strongly reduced. But if they fed the second compound, labeled malonate, the labeled carbon quickly entered the oil.

"From these findings we concluded that the accumulation of the first desaturated fatty acid in the synthesis process inhibits the enzyme that operates at the first step, which converts acetate to malonate," Shanklin said. "That enzyme is Acetyl-CoA carboxylase, or ACCase."

The next step was to make extracts of the tissue culture and directly measure ACCase activity in the test tube. Addition of the suspected slow-down signal provided independent proof that both the signal and target of the signal were correctly identified.

To establish that this feedback mechanism operates in seeds and is not just a weird quirk of the cell-culture setup, the scientists isolated developing canola embryos to test the process. "It worked precisely the same way," Shanklin said.

With the details of the oil production feedback mechanism in hand, Shanklin's team is now exploring how they might interfere with the process, including biochemical schemes to keep the "slow-down" signaling metabolite from accumulating, ways to block its effects on ACCase, and more.

"If we can interrupt this process, we hope to fool the cells so they won't be able to gauge how much oil they have made and will make more," Shanklin said.

###

This research was funded by the DOE Office of Science and Bayer CropScience.

DOE's Office of Science is the single largest supporter of basic research in the physical sciences in the United States, and is working to address some of the most pressing challenges of our time. For more information, please visit: http://science.energy.gov/.

One of ten national laboratories overseen and primarily funded by the Office of Science of the U.S. Department of Energy (DOE), Brookhaven National Laboratory conducts research in the physical, biomedical, and environmental sciences, as well as in energy technologies and national security. Brookhaven Lab also builds and operates major scientific facilities available to university, industry and government researchers. Brookhaven is operated and managed for DOE's Office of Science by Brookhaven Science Associates, a limited-liability company founded by the Research Foundation of State University of New York on behalf of Stony Brook University, the largest academic user of Laboratory facilities, and Battelle, a nonprofit, applied science and technology organization.

Visit Brookhaven Lab's electronic newsroom for links, news archives, graphics, and more at http://www.bnl.gov/newsroom , or follow Brookhaven Lab on Twitter, http://twitter.com/BrookhavenLab .


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Scientists identify mechanism for regulating plant oil production [ Back to EurekAlert! ] Public release date: 4-Jun-2012
[ | E-mail | Share Share ]

Contact: Karen McNulty Walsh
kmcnulty@bnl.gov
631-344-8350
DOE/Brookhaven National Laboratory

Findings suggest ways to increase oil production for biofuels and industrial processes

UPTON, NY - Scientists at the U.S. Department of Energy's Brookhaven National Laboratory have identified key elements in the biochemical mechanism plants use to limit the production of fatty acids. The results suggest ways scientists might target those biochemical pathways to increase the production of plant oils as a renewable resource for biofuels and industrial processes.

"Now that we understand how this system operates - how plants 'know' when they've made enough oil and how they slow down production - we can look for ways to break the feedback loop so they keep making more oil," said Brookhaven biochemist John Shanklin, leader of the group publishing the work in the Proceedings of the National Academy of Sciences the week of June 4, 2012.

Similar biochemical feedback loops regulate a wide range of metabolic processes in living things. They work similar to the way a thermostat maintains a relatively constant temperature in your home: When it gets too warm, the heating system turns off until the temperature falls to the set point, at which time it turns on again.

"There were hints that such a feedback system might exist for plant oil production," said Shanklin, who credits Carl Andre - a former postdoctoral research fellow now working at BASF Plant Science in North Carolina - with designing and carrying out the intricate biochemical detective work that uncovered the details.

"It's very difficult to work on developing oil seeds because they are very tiny," Shanklin explained. So the scientists performed their biochemical tests using a plant embryo cell culture to simulate what goes on in the seeds.

With assistance from the Radiotracer Chemistry and Biological Imaging group at Brookhaven (http://www.bnl.gov/medical/RCIBI/), Andre synthesized "labeled" forms of the fatty acids that occur as intermediates along the metabolic pathway that leads to oil production. He fed these, one at a time, to the plant cell cultures, measuring the labeled metabolites with the help of analytic chemist Richard Haslam of Rothamsted Research in the UK. They also looked to see which added intermediates would inhibit oil production.

Andre's work pointed to a fatty acid that occurs fairly late in the production process, coupled to a carrier protein (essential to making the oily substance soluble in water), as the key intermediate that puts the brakes on oil production. It's the first "desaturated" fatty acid - the first one with a double bond between two of the carbon atoms, formed after all 18 carbon atoms are added to the chain.

Then, knowing that this intermediate somehow sent the "slow-down" signal, the team sought to determine its "target" - how it actually inhibits oil synthesis. They knew from other biochemical feedback loops that the likely target would be an enzyme early in the synthesis pathway. But they wanted to figure out exactly which one.

To do this, they monitored the production process by labeling the intermediates one at a time with a radioactive form of carbon while also feeding the cells an excess of the "slow-down" signaling fatty acid. If the label from the intermediate ended up in the oil product, the "slow-down" signal had to have its effect prior to that step.

The first two experiments gave them the answer: When they labeled the first compound in the synthesis pathway, which is acetate, very little labeled carbon ended up in the oil and oil production was strongly reduced. But if they fed the second compound, labeled malonate, the labeled carbon quickly entered the oil.

"From these findings we concluded that the accumulation of the first desaturated fatty acid in the synthesis process inhibits the enzyme that operates at the first step, which converts acetate to malonate," Shanklin said. "That enzyme is Acetyl-CoA carboxylase, or ACCase."

The next step was to make extracts of the tissue culture and directly measure ACCase activity in the test tube. Addition of the suspected slow-down signal provided independent proof that both the signal and target of the signal were correctly identified.

To establish that this feedback mechanism operates in seeds and is not just a weird quirk of the cell-culture setup, the scientists isolated developing canola embryos to test the process. "It worked precisely the same way," Shanklin said.

With the details of the oil production feedback mechanism in hand, Shanklin's team is now exploring how they might interfere with the process, including biochemical schemes to keep the "slow-down" signaling metabolite from accumulating, ways to block its effects on ACCase, and more.

"If we can interrupt this process, we hope to fool the cells so they won't be able to gauge how much oil they have made and will make more," Shanklin said.

###

This research was funded by the DOE Office of Science and Bayer CropScience.

DOE's Office of Science is the single largest supporter of basic research in the physical sciences in the United States, and is working to address some of the most pressing challenges of our time. For more information, please visit: http://science.energy.gov/.

One of ten national laboratories overseen and primarily funded by the Office of Science of the U.S. Department of Energy (DOE), Brookhaven National Laboratory conducts research in the physical, biomedical, and environmental sciences, as well as in energy technologies and national security. Brookhaven Lab also builds and operates major scientific facilities available to university, industry and government researchers. Brookhaven is operated and managed for DOE's Office of Science by Brookhaven Science Associates, a limited-liability company founded by the Research Foundation of State University of New York on behalf of Stony Brook University, the largest academic user of Laboratory facilities, and Battelle, a nonprofit, applied science and technology organization.

Visit Brookhaven Lab's electronic newsroom for links, news archives, graphics, and more at http://www.bnl.gov/newsroom , or follow Brookhaven Lab on Twitter, http://twitter.com/BrookhavenLab .


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


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